Research Title: 1-Ethyl- 4-hydroxy-2-oxo-1, 2-dihydroquinoline-3-carboxylic acid

Author: Abdul Naseer Dokka, Published Year: 0

Faculty: Pharmacy

Abstract: An X-ray diffraction study of the title compound, C12H11NO4, has shown that this compound exists in the crystal as the 2-oxo-4-hydroxy tautomer. The formation of two O-H O=C-type intermolecular hydrogen bonds leads to the elongation of both exocyclic and carboxylic C=O double bonds involved in the hydrogen bonding, causes shortening of the exocyclic C-O single bond, and also affects the C-C bond lengths in the dihydropyridine ring.

Research Title: 4-Hydroxy-2-quinolines. Synthesis, Structure and antitubercular activity of 4-hydroxy-1-isobutyl-2-oxo-1, 2, 5, 6, 7, 8-hexahydroquinoline-3-carbocylic acid N-R-amides

Author: Abdul Naseer Dokka, Published Year: 0

Faculty: Pharmacy

Abstract: Anilides and hetarylamides-4-1-isobutyl-2-oxo-1, 2, 5, 6, 7, 8-hexahydroquinoline-3-carbocylic acid derivatives have been designed and synthesized for possible anti-mycobacterial action. The preliminary results obtained showed promising antituberecular properties that were greatly affected by the nature of the substituent at the nitrogen atom of quinoline. The features of the spatial structure of the synthesized compounds, as well as their antimicrobial activity against Mycobacterium tuberculosis H37Rv still to be confirmed and analyzed.

Research Title: A novel compound JPM8: in vivo penile activity promotion in rats, effect on the relaxation and cGMP/cAMP accumulation in isolated rabbit corpora cavernosa

Author: Abeer Shnoudeh, Published Year: 2002

International Journal of Impotence Research, 14

Faculty: Pharmacy

Abstract: JPM8 is a novel sildenafil-like PDE5 inhibitor. Its efficacy was tested in vivo by the oral administration of drugs to a rat model and recording penile activity changes. Effect on the relaxation of the rabbit cavernosa was tested in vitro using an organ bath were drugs are added to the tissue media and relaxation was recorded using a transducer connected to a chart recorder. The accumulation of cGMP and cAMP was measured by incubation of cavernosa strips and then extracting the produced cGMP and cAMP in the incubation mixture, then quantitating it using ELISA. JPM8 showed increased and promoted sexual and penile activity in rats in a similar but slightly higher trend than the positive control sildenafil. JPM8 was more efficient in relaxing the rabbit corpora cavernosa than sildenafil. The cGMP and cAMP accumulation showed a similar trend for both drugs. We concluded that JPM8 was very effective in promoting sexual activity in rats, relaxing the corpora cavernosa and promoting cGMP accumulation in rabbits.

Keywords: Phosphodiesterase 5, JPM8, cAMP, cGMP

Research Title: An Approach of Web Services Quality Attributes Specification

Author: Ali Ahmad Alawneh, Published Year: 2010

Communications of IBIMA Journal, 2010

Faculty: Business

Abstract: eb Services are considered a new way of building software applications based on Services that are available through the Internet. However, Web Services still face many problems that are limiting their adoption. One of the causes of this problem is the lack of metadata about the quality attributes of Web Services, which make Service Requesters reluctant to integrate Web Service with their applications. This paper proposes a novel ontology that describes a model of the requester-oriented Web Services' quality attributes. The ontology is based on previous quality models which have been refined and modified specifically to address the quality issues as they relate to the requester of Web Services. Also an analysis will describe how some of the quality attributes in the previous model can be evaluated using different types of test cases.

Keywords: Service Oriented Architecture, Web Services, Quality Attributes, Testing

Research Title: A 5x20 Matrix for Knowledge Management Lifecycle Based on the Five Cs Model and a Critical Review

Author: Ali Ahmad Alawneh, Published Year: 2010

14th International Business Information Management Association (IBIMA) Conference,, Turkey

Faculty: Business

Abstract: Todays organizations invest in various knowledge management systems and tools to enable seamless integration of the constantly increasing volume and sources of information. However, with lack of unified definition of KM and with the presence of different models of KM life cycle, organizations are facing the problem of staying as they are or taking the advantage of implementing KM strategy. In this appear we argue that knowledge management has a life cycle that makes it as an effective strategy, although there are different phases for KM life cycle, still the organization need to understand that KM has an input, process and outcome. In this study, a particular literature review about KM processes has been done to explain the previous efforts that have investigated the models and frameworks of KM lifecycles. Furthermore, the literature addresses different aspects of the fundamental questions about how organizations discover, capture, share, transfer and apply knowledge

Keywords: Knowledge (K), Knowledge Management (KM), Knowledge Management Lifecycle, Five Cs Model, Explicit Knowledge (EK), Tacit Knowledge (TK).

Research Title: An Ontology for the Quality Attributes of web services

Author: Ali Ahmad Alawneh, Published Year: 2009

13th International Business Information Management Association Conference, Morocco

Faculty: Business

Abstract: Web Services are an implementation of Service Oriented Architecture. Web Services applications are built by integration of many loosely coupled heterogeneous Services. Unfortunately Web Services still face many problems that are limiting their growth. A cause of these problems is the lack of metadata about the quality attributes of Web Services. This paper proposes a novel ontology that describes a model of the consumer-oriented Web Services quality attributes. The ontology is based on previous quality models which have been refined and modified specifically to address the quality issues as they relate to the consumer of Web Services. This ontology will also provide a shared understanding about the quality attributes of Web Services among the consumers and providers. Also an analysis will describe how each of the quality attributes in the previous model can be evaluated using different types of test cases.

Keywords: Web Services, Quality Model, Testing, Semantic Web, Ontology

Research Title: An Exploratory Study of the Drivers of E-Business Value Creation in the Jordanian Banking Sector

Author: Ali Ahmad Alawneh, Published Year: 2009

ISIICT 2009 Third International Symposium on Innovation in Information & Communication Technology , Jordan- Philadelphia University

Faculty: Business

Abstract: Based on the Amit and Zott e-Value framework, we have developed an extended conceptual research model for assessing the value of e-business at the bank level. For the purposes of our research some parameters were added to or excluded from e-Value framework since our research is at the national level in Jordanian banking sector. Based on the extended framework, we have formulated four hypotheses and identify four factors (efficiency, complementarities, lock-in, and novelty) that may affect value creation of carrying out e-business in Jordanian banking sector. Survey data from 140 employees in seven pioneered banks in the Jordanian banking sector were collected and used to test the theoretical model. Based on simple and multiple linear regressions, our empirical analysis demonstrates several key findings: (1) Together, the efficiency, complementarities, lock-in and novelty factors strengthen e-business value as the hypotheses are supported. (2) the novelty is the strongest driver for e-business value creation than the other drivers efficiency, lock-in and complementarities (3) all of the drivers efficiency, complementarities, lock-in and novelty explain to the high degree the variance of sales-services-marketing as a dimension of e-business value, then to the middle degree the variance of internal operations as a dimension of e-business value, and to the low degree the variance of coordination and communication as a dimension of e-business value. These findings indicate the usefulness of the proposed research model for studying e-business value in banks. They also provide insights for both business managers and policy-makers to betterment the bank performance in terms of sales-services-marketing; internal operations and coordination & communication.

Keywords: e-business, e-business value, drivers of value creation, e-Value framework, bank performance, e-banking, Jordanian banking sector

Research Title: Some Topics in E-Government

Author: Ali Ahmad Alawneh, Published Year: 2009

the Second International Conference on Information and Communication technology & Accessibility, Tunsia

Faculty: Business

Abstract: As we know one of the most popular aspects in our time is E-Government .The purpose of this paper is to specify a Security in E-government, Directions in e- Government and to give some factors that show the effectiveness and restrictions of the e-government and its different aspects like (Defining the concepts of the E- Government, the readiness of the infrastructure, human resource (HR) capability and competency).

Keywords: E- Government, readiness, infrastructure, human resource (HR) capability, competency

Research Title: An Empirical Syudy of the Sources Affecting E-Business Value Creation in Jordanian Banking Services Sector

Author: Ali Ahmad Alawneh, Published Year: 2009

The International Arab Journal of e-Technology (IAJeT). , 1(2)

Faculty: Business

Abstract: Grounded in the technology–organization–environment (TOE) framework, we have developed an extended conceptual research model for assessing the value of e-business at the bank level. For the purposes of our research some constructs were added to (TOE) framework such as IT/Business strategy alignment, adequacy of IT professionals, and availability of online revenues. Other factors were excluded such as the global scope since our research is at the national level in Jordanian banking sector. Based on our enhanced framework, we have formulated eight hypotheses and identify eight factors (technology readiness or competence, bank size, financial resources commitment, IT/Business strategy alignment, adequacy of IT professionals, availability of online revenues, competition intensity or pressure, and regulatory support environment) that may affect value creation of carrying out e-business in Jordanian banking sector. Survey data from 140 employees in seven pioneered banks in the Jordanian banking services industry were collected and used to test the theoretical model. Based on simple and multiple linear regressions, our empirical analysis demonstrates several key findings: (1) technology readiness is found to have the strongest significant influence on the e-business value in banks. (2) Bank size, IT/Business strategy alignment, and availability of online revenues are found to have significant influence on the e-business value in banks, while financial resources commitment and adequacy of IT professionals do not contribute significantly to e-business value. (3) Both the competition intensity and regulatory support environment contribute significantly to value creation of e-business in banks. These findings indicate the usefulness of the proposed research model for studying e-business value in banks. They also provide insights for both business managers and policy-makers.

Keywords: e-business, e-business value, sources of value creation, technology-organization-environment (TOE) framework, bank performance, e-banking, Jordanian banking industry.

Research Title: E-Banking Diffusion in the Jordanian Banking Services Sector: An Empirical Analysis of Key Factors

Author: Ali Ahmad Alawneh, Published Year: 2009

", International Journal of Actor-Network Theory and Technological Innovation, 1(2)

Faculty: Business

Abstract: Grounded in the technology–organization–environment (TOE) framework, we have developed an extended model to examine factors, particularly technological, organizational and environmental factors, which influence e-banking adoption in Jordanian banks. This article added some constructs to (TOE) framework, other factors were excluded. The independent variables are the (technology readiness or competence, bank size, financial resources commitment, IT/Business strategy alignment, adequacy of IT professionals, availability of online revenues, competition intensity or pressure, and regulatory support environment) while e-banking usage constitutes the dependent variable. Our empirical analysis demonstrates several key findings related to the technological, organizational, and environmental aspects of the banks. This article can help further understanding of their role in the adoption of e-banking and examines the impacts of e-banking usage on banks’ performance in terms of sales-services-marketing, internal operations and coordination & communication. This could enable greater e-banking usage that could improve the overall economy

Keywords: technology–organization–environment (TOE) framework, adoption of e-banking, technology readiness or competence, bank size, financial resources commitment, IT/Business strategy alignment, adequacy of IT professionals, availability of online revenues, competition intensity or pressure, and regulatory support environment)