Research Title: Pathways to Mainstream and Advance the Concept of Global Citizenship Education in the Arab World, Global Citizenship foundation, 2022

Author: Amani Ghazi Jarrar, Published Year: 2021

Faculty: Arts

Abstract: Thinkers and planners for education and higher education agreed on the need for education to serve global citizenship as a potent force in bringing economic, social, and political change, and in enabling the nation to face challenges, and this is clearly affirmed through education for human rights and world education for global citizenship. One can divide the Arab thinkers into five categories, each with a point of view different from the other (Altbach, 1999). The first category of Arab intellectual's rejectionists, who believe that globalization, reflects the higher stages of colonialism created by the technological revolution and information that dominates the capitalist market, as governed by the United States and Western countries. (Jarrar, 2012). The second category of Arab intellectuals is those who welcome globalization. The third category of Arab intellectuals represents the neutral position, which calls for finding an appropriate form of globalization consistent with the interests and aspirations of the Arab countries. The fourth category of Arab intellectuals represents a positive vision being pragmatic and utilitarian (Muasher & Faour, 2011). They think of globalization as a historical phenomenon that Arab nations should treat with caution and prudence. Globalization emphasizes the sovereignty of Arab intellectuals and establishes the Arab cultural identity in order to spread the values of tolerance. https://www.globalcitizenshipfoundation.org/article/pathways-to-mainstream-and-advance-the-concept-of-global-citizenship-education-in-the-arab-world

Keywords: Global Citizenship ,Education,Arab World

Research Title: Global Citizenship and Education for Peace

Author: Amani Ghazi Jarrar, Published Year: 2021

Faculty: Arts

Abstract: Peace is a human goal and a noble aspiration towards humanity has been trying to achieve throughout its cultural history. The call for peace, laying down its foundation, and spreading it worldwide has gained momentum in the modern age as a means of creating a rallying point around which the mutual understanding of all peoples of the world may revolve. Peace studies became an area of academic research in universities worldwide in the 1950s. At the onset, the focus was on peace vis-à-vis direct violence, as it is the case with aggression, torture, persecution, and wars. Later, research expanded to tackle indirect violence, i.e., human suffering under social, political, and economic systems that lead to death or belittling people’s dignity and violation of their rights. Racial discrimination, exposure to famine, and denial of human rights are typical examples. Speaking of “education,” it is an invitation to live—and life, in essence, is peace with self, with others, and with the environment. Hence, education for peace ranges in its expanse from peace among nations and peoples, to individual peace in the family or community and, ultimately, to the inner peace of the individual him/herself. https://burhaninstitute.org/?p=1071

Keywords: Global Citizenship , Education , Peace

Research Title: TOWARDS SOCIAL JUSTICE AND GLOBAL CITIZENSHIP AS AN INTELLECTUAL APPROACH AND GLOBAL ASPIRATION FOR HUMANITY (IN A STRIFE-RIDDEN WORLD)

Author: Amani Ghazi Jarrar, Published Year: 2021

Faculty: Arts

Abstract: In today’s world, we encounter a great number of exacerbating conflicts and crises that may even lead to annihilation of human life on this planet, if they are allowed to persist. Into whatever direction we turn, we witness raging fateful North/South and East/West struggles. However, nothing would enable us to overcome such ongoing political conflicts, economic crises, environmental catastrophes or social afflictions other than using a great panacea and supreme instrument of this equation – that is, to put the necessary human principles in place. Whosoever believes in the oneness of humanity – irrespective of the multiplicity and diversity of its parties, regions, and warring factions – finds nothing at the core, save that essentially indivisible human spirit, notwithstanding the diversity of ethnicity, creeds, denominations, ideologies, and interests. Back in the day, the Chinese philosopher Confucius called for the principle of inner peace, and he was followed down through the ages by other expositions, from leaders of thought, of the beneficial effects of establishing peace in solving countless human problems and disputes. In this hypothesis, I will attempt to add to the foundation that those prior advocates of peace had laid down, by establishing that principle of the consciousness of global citizenship is a modern-day panacea for current and future crises and conflicts. https://burhaninstitute.org/?p=1044

Keywords: Social Justice , Global Citizenship, humanity

Research Title: المواطنة العالمية والتربية من أجل السلام

Author: Amani Ghazi Jarrar, Published Year: 2021

Faculty: Arts

Abstract: السلام هدف إنساني وغاية نبيلة تسعى الإنسانية لتحقيقها على امتداد تاريخها الحضاري، وقد ازدادت الدعوة للسلام والعمل على إرساء دعائمه وتعميمه في العصر الحديث كأداة تفاهم تجمع شعوب العالم حول هذا الهدف. لقد بدأ الاهتمام بدراسات السلام كميدان أكاديمي في الجامعات العالمية منذ الخمسينات، وكان التركيز في البداية على السلام في مواجهة العنف المباشر، كما هو الحال في الاعتداء والتعذيب والاضطهاد والحروب، ليتطور فيما بعد إلى تناول العنف غير المباشر، أي ما يعانيه الناس نتيجة للنظم الاجتماعية والسياسية والاقتصادية التي تؤدي إلى الموت أو الانتقاص من آدمية الإنسان وانتهاك حقوقه مثل : التمييز العنصري والتعرض للجوع وإنكار حقوق الإنسان. والتربية دعوة للحياة، والحياة في جوهرها هي السلام مع الذات ومع الآخرين ومع البيئة المادية، ومن هنا فإن التربية من أجل السلام تتراوح في مداها من السلام بين الدول والشعوب إلى الأفراد داخل الأسرة أو الجماعة وأخيراً إلى الإنسان نفسه. https://burhaninstitute.org/?p=1050

Keywords: مواطنة عالمية ، تربية ،سلام

Research Title: السعي نحو العدالة الاجتماعية والمواطنة العالمية كمنهج فكري وطموح عالمي للإنسانية

Author: Amani Ghazi Jarrar, Published Year: 2021

Faculty: Arts

Abstract: في عالمنا اليوم نلمس الكثير من الصراعات والأزمات المتنامية نحو هلاك البشرية اذا ما كتب لها الاستمرار. فأينما نظرنا نجد صراعات مصيرية بين الشمال والجنوب والشرق والغرب. وما من قادر على حل المنازعات السياسية والازمات الاقتصادية المتنازع عليها والكوارث البيئية والاجتماعية، الا وان يلجأ الى حلول العامل السحري المنقذ الأعظم في هذه المعادلة، ألا وهو احلال مبادىء الإنسانية ، فمن آمن بوحدتها على الرغم من تعدد الأطراف والجهات والمتنازعين، لا يجد سوى روح الانسانية لتبقى واحدة في الجوهر مهما اختلفت الأعراق والمذاهب والطوائف والايديولوجيات والمصالح. https://burhaninstitute.org/?p=930

Keywords: عدالة اجتماعية ، مواطنة عالمية ، فكؤ ،انسان

Research Title: Development and Characterization of Econazole Topical Gel

Author: Balakumar Chandrasekarn, Published Year: 2023

GELS, 9

Faculty: Pharmacy

Abstract: The purpose of this work was to develop a novel topical formulation of econazole nitrate based on gel that can be easily scaled up in one pot for the potential treatment of fungal and yeast infections. Econazole nitrate, a topical antifungal, is used to treat tinea versicolor, tinea pedis, and tinea cruris. Compared to applying cream or ointment, topical gels offer numerous advantages, one of which is that the drug is released more quickly to the intended site of action. A viscous mixture of propylene glycol, Capmul® MCM C8, methyl and propyl paraben, and econazole nitrate were mixed together before being formulated into the optimized Carbopol® gel bases. The gel’s color, appearance, and homogeneity were assessed visually. For every formulation, the drug content, pH, viscosity, spreadability, and gel strength were characterized. The cup plate diffusion method was used to evaluate the anti-fungal activity of the prepared formulations. To assess the behavior of the developed system, studies on in vitro release and mechanism were conducted. The manufactured formulations were transparent, pale yellow, and exhibited excellent homogeneity. The pH of each formulation was roughly 6.0, making them suitable for topical use. The concentration of Carbopol® 940 resulted in a significant increase in viscosity and gel strength but a significant decrease in spreadability. It was demonstrated that the prepared formulations inhibited the growth of Candida albicans and Aspergillus fumigatus. In contrast, the standard blank gel showed no signs of antifungal action. By increasing the concentration of Carbopol® 940, the in vitro release profile of econazole nitrate significantly decreased. Following the Korsmeyer–Peppas model fitting, all formulations exhibited n values greater than 0.5 and less than 1, indicating that diffusion and gel swelling control econazole nitrate release.

Keywords: econazole; cutaneous candidiasis; Carbopol® 940; topical gel; sustainability

Research Title: Design, Synthesis, Anticancer Screening and Molecular Modelling Studies of Novel Thiazoles

Author: Balakumar Chandrasekarn, Published Year: 2023

ChemistrySelect, 8

Faculty: Pharmacy

Abstract: A library of novel benzamide-thiazolyl-chalcone compounds was synthesized via Claisen-Schmidt reaction and spectroscopically characterized using FT-IR, 1H-NMR, 13C-NMR, LC–MS, and HR-MS. The synthesized compounds were biologically evaluated using in vitro MTT assay against different cancer cell lines (MCF-7, MDA-AMB-231, Caco-2, A549, and H1299). Amongst all compounds screened, (E)-N-(5-(3-(4-hydroxyphenyl)-3-oxoprop-1-en-1-yl)thiazol-2-yl)benzamide and (E)-N-(5-(3-(4-methoxyphenyl)-3-oxoprop-1-en-1-yl)thiazol-2-yl)benzamide showed potent anti-proliferation against breast (MCF-7) and colon cancer cell lines reaching 88.56 % and 84.36 % with IC50 values of 44.00 μM and 58.88 μM, respectively. All synthesized compounds exhibited no significant cytotoxicity to normal cells. Structure-activity relationship studies demonstrated the effect of electron-donating and electron-withdrawing groups on the anticancer activity of the molecules under investigation. This was also corroborated by theoretical DFT studies. Thus, these molecules may serve as potential lead candidates for further development of novel anticancer agents against breast and colon cancers.

Keywords: Thiazoles, Synthesis, Anticancer Screening Molecular docking

Research Title: Target protein degradation by protacs: a budding cancer treatment strategy

Author: Balakumar Chandrasekarn, Published Year: 2023

Pharmacology & Therapeutics, 250

Faculty: Pharmacy

Abstract: Cancer is one of the most common causes of death. So, its lethal effect increases with time. Near about hundreds of cancers are known in humans. Cancer treatment is done to cure or prolonged remission, and shrinkage of the tumor. Cytotoxic agents, biological agents/targeted drugs, hormonal drugs, surgery, radiotherapy/proton therapy, chemotherapy, immunotherapy, and gene therapy are currently used in the treatment of cancer but their cost is high and cause various side effects. Seeing this, some new targeted strategies such as PROTACs are the need of the time. Proteolysis targeting chimera (PROTAC) has become one of the most discussed topics regarding cancer treatment. Few of the PROTAC molecules are in the trial phases. PROTACs have many advantages over other strategies such as modularity, compatibility, sub-stoichiometric activity, acting on undruggable targets, molecular design, and acts on intracellular targets, selectivity and specificity can be recruited for any cancer, versatility, and others. PROTACs are having some unclear questions on their pharmacokinetics, heavy-molecular weight, etc. PROTACs are anticipated to bring about a conversion in current healthcare and will emerge as booming treatments. In this review article we summarize PROTACs, their mechanism of action, uses, advantages, disadvantages, challenges, and future aspects for the successful development of potent PROTACs as a drug strategy.

Keywords: protacs cancer treatment

Research Title: Performance Comparison of Four-Stroke Diesel Engine Fuelled by Various Biodiesel Blends and Diesel

Author: Mustafa Awwad Al Khawaldeh, Published Year: 2023

Advances in Science and Technology Research Journal, 17

Faculty: Engineering and Technology

Abstract: The objective of this study is to compare the performance of diesel engines, fuelled with biofuel blends extracted from corn, sunflower, and palm oils, against pure diesel. The experiments were performed using Lister LVI, single-cylinder, direct injection, four-stroke engines, with a compression ratio of 17:1. The following parameters were analysed: brake torque, brake mean effective pressure (BMEP), brake specific fuel consumption (BSFC), brake thermal efficiency, and exhaust gas temperature. The findings indicate that the characteristics of biodiesels are close to diesel fuel. Therefore, biodiesel becomes a viable alternative to diesel fuel without any modifications. Pure diesel has higher brake thermal efficiency and lower BSFC than all the biodiesel blends tested in this study. In addition, the engine consumes less fuel for biodiesel blends than pure diesel. High exhaust temperatures are conducive to nitrogen oxides (NOx) generation; hence, this study reveals that the exhaust temperature is reduced when utilizing biodiesel compared to pure diesel. According to several tests, palm biodiesel provides greater torque and BMEP than the rest of the biodiesel blends, and pure diesel due to emitting less NOx. Therefore, it stands to reason that it would be utilized in a diesel engine.

Keywords: biodiesel, diesel engine, performance, comparison, vegetable oils

Research Title: Mitigating the carbon footprint in Jordan by designing an artificial lake system to improve domestic tourism

Author: Mustafa Awwad Al Khawaldeh, Published Year: 2023

Results in Engineering, 20

Faculty: Engineering and Technology

Abstract: Abstract This work investigates mitigating the carbon footprint in Jordan by altering the travel patterns of the population. This goal can be accomplished by creating a new tourist destination that has a marine environment, similar to overseas destinations. Based on recent data, it is estimated that half a million Jordanians would prefer a domestic destination instead of traveling abroad, provided that it has a marine environment. This shift in travel preferences would result in an estimated reduction of 320,000 tons of CO2 emissions every year. The proposed new destination is an artificial lake created in the Jafer basin, located in southeastern Jordan. The area has a natural depression that is suitable for this purpose. The proposal involves excavating a 140 km-long tunnel connecting the Gulf of Aqaba to the Jafer basin, where seawater is pumped into the basin to create the lake, with a water volume of 2000 MCM. The design is based on keeping the water's level steady in the lake. The proposed design is shown to be feasible, with an optimal tunnel diameter of 4 m, excavated at constant depth. In order to maintain a uniform water pressure, 15 pumping stations should be installed along the tunnel. The total cost of the project is estimated at 5.5 B$. This cost is not only used for mitigating carbon footprint but also for increasing the real estate value of the area around the lake, and a more healthy distribution of population in the country.

Keywords: Artificial lake engineering design; Carbon footprint; Domestic tourism; Jafer basin; Pumping station