Research Title: Political Concepts in Jordanian Schools Curricula of the Scientific and Literary Streams ( Grades 11th and 12th)

Author: Amani Ghazi Jarrar, Published Year: 2014

Elsevier, Procedia-Social and Behavioural Journal , www.wces.info , 116

Faculty: Arts

Abstract: The study aims at identifying political concepts in Jordanian schools curricula for grades 11th and 12th in the scientific and literary streams .Books were analyzed according to the content analysis approach. The results showed that political concepts were more obvious in the 12th grade of the literary stream if compared to the 11th grade. It was concluded that more attention to political concepts should be given in the scientific stream in order to contribute to developing students' political understanding, so as to be able to deal with global issues, in addition to teaching concepts renouncing ideological extremism. The study recommends that more quality political concepts should be introduced in the scientific stream curricula. https://pdf.sciencedirectassets.com/277811/1-s2.0-S1877042814X00108/1-s2.0-S1877042814002146/main.pdf?X-Amz-Security-Token=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&X-Amz-Algorithm=AWS4-HMAC-SHA256&X-Amz-Date=20231211T130713Z&X-Amz-SignedHeaders=host&X-Amz-Expires=300&X-Amz-Credential=ASIAQ3PHCVTYZKCYVO7N/20231211/us-east-1/s3/aws4_request&X-Amz-Signature=43c843f4db62e136a5746cff2e8d1c6eb07ca603d785eadb437dae815276d279&hash=dda330340436eb354cf76d24dbf72605b98dc8d8f10d62a15f5074fbe97b909a&host=68042c943591013ac2b2430a89b270f6af2c76d8dfd086a07176afe7c76c2c61&pii=S1877042814002146&tid=spdf-deb6e9f2-1692-49ef-80ec-d5ed7cc37c4a&sid=6e52694930cfe34c464bb087b33ec49a5c83gxrqb&type=client&tsoh=d3d3LnNjaWVuY2VkaXJlY3QuY29t&ua=10095e545d0b0452535507&rr=833df304f86232ae&cc=jo

Keywords: Political concepts, School curricula , Content analysis,Scientific stream, Literary stream, Education in Jordan.

Research Title: Global Citizenship Education in Jordanian Universities

Author: Amani Ghazi Jarrar, Published Year: 2012

Procedia Social and Behavioral Sciences Journal , 47

Faculty: Arts

Abstract: This paper is an attempt to establish the foundations of education for global citizenship. It is mainly built on four themes: world citizenship education, key issues and challenges of contemporary human thought, philosophical and analytical approach, and then an attempt for global citizenship educational planning. This paper uses a descriptive qualitative approach in considering as Jordanian case study, in terms of the philosophy of National Education of Jordan. The paper concludes with the suggestion that to achieve the humanitarian component of global citizenship in education, one must start from the moral value system of human identity. https://pdf.sciencedirectassets.com/277811/1-s2.0-S1877042812X00181/1-s2.0-S1877042812026602/main.pdf?X-Amz-Security-Token=IQoJb3JpZ2luX2VjEJz//////////wEaCXVzLWVhc3QtMSJGMEQCIDXYYCCUC5fvLtmaruyTxbdXpjUNjkhJ3suhYsP+HUHuAiBO74r2O6468AV7tYGfEMUDPxnLea9nAo99VwdsuaTJCCqzBQgVEAUaDDA1OTAwMzU0Njg2NSIMqLY5njMdxvHDuXoSKpAFXZSAFlSh5UR1eZQOwa7lxJtWdUQCjN4isYuLr9eJmAIkw611+0hOgoxkBKTPrHlIk8cdq8cB98alLpebLMDd5EpIsbMx3v/Ojx6XEPyW/oRN279RxRL+g7TpA9wiH0VeN0cQOFM4AnuJ8TM8VODCTyx30CPc+dKYHFDblYGQi7/gkwT426xXqzpRXlgdrRJy963arSYgzDLfRTN2fbV+Oevo7TeYp/8xuYqp3L8WGFEMCh1uVYUNT8rAOZt/nBTpn5wKkr1VhJo3/WZAyJ2QAoNuNQ5h/TiZwcJkMJgJRfHbavJUomiQXdLMW/UFhUvOXggGbIJ0yjlnRnjzi75y4s2YWnZCRC6wssCFua34SYX4CVyS9aD6+57jyZZAtXzEqXnsBj8kIOSsROlxhtKCDazFY9hsPI6pS6YUa5Qra9iF1G3+L7IgRSbOen+ZDUgvYADqB5weMiJqaylmH3mniPUWJbXsgiu0finCCcNDOp+Hg44Lp0twKN5LqOkaj68Ansq8tGtan3/YZL6b75aZdErsTfCyylm2wOWZaV8+tujqID1P+AmBeBOigT0pE0rOvZyLy3MO4xGK7VC+5VLF5f2Dv9ENJFs//daPvPZPHA/BUfQh3ltSmcyLsDp7F4jcMR6pybxdU+8e8hnF9AwzPb1ZrlUl8UnW03bJkBmfI35R2bSc2c44yFjrQ0UVxf5+daatQEkjom6jl80AlM3giYpUDYS+YjR6FPL23REkIXCABpUQf9Kj7+2wkf02nTj1kHtSPwCpRmzCPypVluKvm1hl7Ck/uLoZNh4DOG2mHUHnifz6XBIhOKqGnqADgzkYk4dD3iLE8kbmV/le72+SowNlgOctO8sdZj6vslPlO+Ewt+3bqwY6sgGcvWhCYyzH2YEtgeG2KoLkEciB2unk32Bh2BCYmWXVbYil9iXugAIh7lQRE7g2VyxWQJTRgNpro4URgKFaT4CNOeGe5W0W51r+qhnZnPZBvJUDLT1juXMjOwYuFBIbfShUgeeMRuaA03j04xRKKEVRg6Ek5sRofyFagXErkgOW4qBOIPLLnSBGb1944lvDr89wblruFOcZJl34xHhWJ/uN1aPPqPPZ0qXc+Uq0cSnzSKEg&X-Amz-Algorithm=AWS4-HMAC-SHA256&X-Amz-Date=20231211T123359Z&X-Amz-SignedHeaders=host&X-Amz-Expires=300&X-Amz-Credential=ASIAQ3PHCVTYVVPTLZWR/20231211/us-east-1/s3/aws4_request&X-Amz-Signature=42ebea6fe029cacab2c54f978925c2faf295b500963c2badf6f11f002f521779&hash=c9018f1d53c3928ced7c6f7279babcb0f43d71608b054e10016799492b7a8ef1&host=68042c943591013ac2b2430a89b270f6af2c76d8dfd086a07176afe7c76c2c61&pii=S1877042812026602&tid=spdf-29f1fa1e-f192-42ff-beb5-a373aa6cf1e7&sid=6e52694930cfe34c464bb087b33ec49a5c83gxrqb&type=client&tsoh=d3d3LnNjaWVuY2VkaXJlY3QuY29t&ua=10095e545d0b0153565700&rr=833dc256ac8732ad&cc=jo

Keywords: Global citizenship education, national education, civic education, human rights education, Jordan.

Research Title: Pathways to Mainstream and Advance the Concept of Global Citizenship Education in the Arab World, Global Citizenship foundation, 2022

Author: Amani Ghazi Jarrar, Published Year: 2021

Faculty: Arts

Abstract: Thinkers and planners for education and higher education agreed on the need for education to serve global citizenship as a potent force in bringing economic, social, and political change, and in enabling the nation to face challenges, and this is clearly affirmed through education for human rights and world education for global citizenship. One can divide the Arab thinkers into five categories, each with a point of view different from the other (Altbach, 1999). The first category of Arab intellectual's rejectionists, who believe that globalization, reflects the higher stages of colonialism created by the technological revolution and information that dominates the capitalist market, as governed by the United States and Western countries. (Jarrar, 2012). The second category of Arab intellectuals is those who welcome globalization. The third category of Arab intellectuals represents the neutral position, which calls for finding an appropriate form of globalization consistent with the interests and aspirations of the Arab countries. The fourth category of Arab intellectuals represents a positive vision being pragmatic and utilitarian (Muasher & Faour, 2011). They think of globalization as a historical phenomenon that Arab nations should treat with caution and prudence. Globalization emphasizes the sovereignty of Arab intellectuals and establishes the Arab cultural identity in order to spread the values of tolerance. https://www.globalcitizenshipfoundation.org/article/pathways-to-mainstream-and-advance-the-concept-of-global-citizenship-education-in-the-arab-world

Keywords: Global Citizenship ,Education,Arab World

Research Title: Global Citizenship and Education for Peace

Author: Amani Ghazi Jarrar, Published Year: 2021

Faculty: Arts

Abstract: Peace is a human goal and a noble aspiration towards humanity has been trying to achieve throughout its cultural history. The call for peace, laying down its foundation, and spreading it worldwide has gained momentum in the modern age as a means of creating a rallying point around which the mutual understanding of all peoples of the world may revolve. Peace studies became an area of academic research in universities worldwide in the 1950s. At the onset, the focus was on peace vis-à-vis direct violence, as it is the case with aggression, torture, persecution, and wars. Later, research expanded to tackle indirect violence, i.e., human suffering under social, political, and economic systems that lead to death or belittling people’s dignity and violation of their rights. Racial discrimination, exposure to famine, and denial of human rights are typical examples. Speaking of “education,” it is an invitation to live—and life, in essence, is peace with self, with others, and with the environment. Hence, education for peace ranges in its expanse from peace among nations and peoples, to individual peace in the family or community and, ultimately, to the inner peace of the individual him/herself. https://burhaninstitute.org/?p=1071

Keywords: Global Citizenship , Education , Peace

Research Title: TOWARDS SOCIAL JUSTICE AND GLOBAL CITIZENSHIP AS AN INTELLECTUAL APPROACH AND GLOBAL ASPIRATION FOR HUMANITY (IN A STRIFE-RIDDEN WORLD)

Author: Amani Ghazi Jarrar, Published Year: 2021

Faculty: Arts

Abstract: In today’s world, we encounter a great number of exacerbating conflicts and crises that may even lead to annihilation of human life on this planet, if they are allowed to persist. Into whatever direction we turn, we witness raging fateful North/South and East/West struggles. However, nothing would enable us to overcome such ongoing political conflicts, economic crises, environmental catastrophes or social afflictions other than using a great panacea and supreme instrument of this equation – that is, to put the necessary human principles in place. Whosoever believes in the oneness of humanity – irrespective of the multiplicity and diversity of its parties, regions, and warring factions – finds nothing at the core, save that essentially indivisible human spirit, notwithstanding the diversity of ethnicity, creeds, denominations, ideologies, and interests. Back in the day, the Chinese philosopher Confucius called for the principle of inner peace, and he was followed down through the ages by other expositions, from leaders of thought, of the beneficial effects of establishing peace in solving countless human problems and disputes. In this hypothesis, I will attempt to add to the foundation that those prior advocates of peace had laid down, by establishing that principle of the consciousness of global citizenship is a modern-day panacea for current and future crises and conflicts. https://burhaninstitute.org/?p=1044

Keywords: Social Justice , Global Citizenship, humanity

Research Title: المواطنة العالمية والتربية من أجل السلام

Author: Amani Ghazi Jarrar, Published Year: 2021

Faculty: Arts

Abstract: السلام هدف إنساني وغاية نبيلة تسعى الإنسانية لتحقيقها على امتداد تاريخها الحضاري، وقد ازدادت الدعوة للسلام والعمل على إرساء دعائمه وتعميمه في العصر الحديث كأداة تفاهم تجمع شعوب العالم حول هذا الهدف. لقد بدأ الاهتمام بدراسات السلام كميدان أكاديمي في الجامعات العالمية منذ الخمسينات، وكان التركيز في البداية على السلام في مواجهة العنف المباشر، كما هو الحال في الاعتداء والتعذيب والاضطهاد والحروب، ليتطور فيما بعد إلى تناول العنف غير المباشر، أي ما يعانيه الناس نتيجة للنظم الاجتماعية والسياسية والاقتصادية التي تؤدي إلى الموت أو الانتقاص من آدمية الإنسان وانتهاك حقوقه مثل : التمييز العنصري والتعرض للجوع وإنكار حقوق الإنسان. والتربية دعوة للحياة، والحياة في جوهرها هي السلام مع الذات ومع الآخرين ومع البيئة المادية، ومن هنا فإن التربية من أجل السلام تتراوح في مداها من السلام بين الدول والشعوب إلى الأفراد داخل الأسرة أو الجماعة وأخيراً إلى الإنسان نفسه. https://burhaninstitute.org/?p=1050

Keywords: مواطنة عالمية ، تربية ،سلام

Research Title: السعي نحو العدالة الاجتماعية والمواطنة العالمية كمنهج فكري وطموح عالمي للإنسانية

Author: Amani Ghazi Jarrar, Published Year: 2021

Faculty: Arts

Abstract: في عالمنا اليوم نلمس الكثير من الصراعات والأزمات المتنامية نحو هلاك البشرية اذا ما كتب لها الاستمرار. فأينما نظرنا نجد صراعات مصيرية بين الشمال والجنوب والشرق والغرب. وما من قادر على حل المنازعات السياسية والازمات الاقتصادية المتنازع عليها والكوارث البيئية والاجتماعية، الا وان يلجأ الى حلول العامل السحري المنقذ الأعظم في هذه المعادلة، ألا وهو احلال مبادىء الإنسانية ، فمن آمن بوحدتها على الرغم من تعدد الأطراف والجهات والمتنازعين، لا يجد سوى روح الانسانية لتبقى واحدة في الجوهر مهما اختلفت الأعراق والمذاهب والطوائف والايديولوجيات والمصالح. https://burhaninstitute.org/?p=930

Keywords: عدالة اجتماعية ، مواطنة عالمية ، فكؤ ،انسان

Research Title: Development and Characterization of Econazole Topical Gel

Author: Balakumar Chandrasekarn, Published Year: 2023

GELS, 9

Faculty: Pharmacy

Abstract: The purpose of this work was to develop a novel topical formulation of econazole nitrate based on gel that can be easily scaled up in one pot for the potential treatment of fungal and yeast infections. Econazole nitrate, a topical antifungal, is used to treat tinea versicolor, tinea pedis, and tinea cruris. Compared to applying cream or ointment, topical gels offer numerous advantages, one of which is that the drug is released more quickly to the intended site of action. A viscous mixture of propylene glycol, Capmul® MCM C8, methyl and propyl paraben, and econazole nitrate were mixed together before being formulated into the optimized Carbopol® gel bases. The gel’s color, appearance, and homogeneity were assessed visually. For every formulation, the drug content, pH, viscosity, spreadability, and gel strength were characterized. The cup plate diffusion method was used to evaluate the anti-fungal activity of the prepared formulations. To assess the behavior of the developed system, studies on in vitro release and mechanism were conducted. The manufactured formulations were transparent, pale yellow, and exhibited excellent homogeneity. The pH of each formulation was roughly 6.0, making them suitable for topical use. The concentration of Carbopol® 940 resulted in a significant increase in viscosity and gel strength but a significant decrease in spreadability. It was demonstrated that the prepared formulations inhibited the growth of Candida albicans and Aspergillus fumigatus. In contrast, the standard blank gel showed no signs of antifungal action. By increasing the concentration of Carbopol® 940, the in vitro release profile of econazole nitrate significantly decreased. Following the Korsmeyer–Peppas model fitting, all formulations exhibited n values greater than 0.5 and less than 1, indicating that diffusion and gel swelling control econazole nitrate release.

Keywords: econazole; cutaneous candidiasis; Carbopol® 940; topical gel; sustainability

Research Title: Design, Synthesis, Anticancer Screening and Molecular Modelling Studies of Novel Thiazoles

Author: Balakumar Chandrasekarn, Published Year: 2023

ChemistrySelect, 8

Faculty: Pharmacy

Abstract: A library of novel benzamide-thiazolyl-chalcone compounds was synthesized via Claisen-Schmidt reaction and spectroscopically characterized using FT-IR, 1H-NMR, 13C-NMR, LC–MS, and HR-MS. The synthesized compounds were biologically evaluated using in vitro MTT assay against different cancer cell lines (MCF-7, MDA-AMB-231, Caco-2, A549, and H1299). Amongst all compounds screened, (E)-N-(5-(3-(4-hydroxyphenyl)-3-oxoprop-1-en-1-yl)thiazol-2-yl)benzamide and (E)-N-(5-(3-(4-methoxyphenyl)-3-oxoprop-1-en-1-yl)thiazol-2-yl)benzamide showed potent anti-proliferation against breast (MCF-7) and colon cancer cell lines reaching 88.56 % and 84.36 % with IC50 values of 44.00 μM and 58.88 μM, respectively. All synthesized compounds exhibited no significant cytotoxicity to normal cells. Structure-activity relationship studies demonstrated the effect of electron-donating and electron-withdrawing groups on the anticancer activity of the molecules under investigation. This was also corroborated by theoretical DFT studies. Thus, these molecules may serve as potential lead candidates for further development of novel anticancer agents against breast and colon cancers.

Keywords: Thiazoles, Synthesis, Anticancer Screening Molecular docking

Research Title: Target protein degradation by protacs: a budding cancer treatment strategy

Author: Balakumar Chandrasekarn, Published Year: 2023

Pharmacology & Therapeutics, 250

Faculty: Pharmacy

Abstract: Cancer is one of the most common causes of death. So, its lethal effect increases with time. Near about hundreds of cancers are known in humans. Cancer treatment is done to cure or prolonged remission, and shrinkage of the tumor. Cytotoxic agents, biological agents/targeted drugs, hormonal drugs, surgery, radiotherapy/proton therapy, chemotherapy, immunotherapy, and gene therapy are currently used in the treatment of cancer but their cost is high and cause various side effects. Seeing this, some new targeted strategies such as PROTACs are the need of the time. Proteolysis targeting chimera (PROTAC) has become one of the most discussed topics regarding cancer treatment. Few of the PROTAC molecules are in the trial phases. PROTACs have many advantages over other strategies such as modularity, compatibility, sub-stoichiometric activity, acting on undruggable targets, molecular design, and acts on intracellular targets, selectivity and specificity can be recruited for any cancer, versatility, and others. PROTACs are having some unclear questions on their pharmacokinetics, heavy-molecular weight, etc. PROTACs are anticipated to bring about a conversion in current healthcare and will emerge as booming treatments. In this review article we summarize PROTACs, their mechanism of action, uses, advantages, disadvantages, challenges, and future aspects for the successful development of potent PROTACs as a drug strategy.

Keywords: protacs cancer treatment