Research Title: Wuhan ou la Naissance de la Covid 19 (2022) de Mohammed Becha: Un Document sur cette Pandémie et une Histoire d’amour †

Author: Mohammad Al-Ghazu, Published Year: 2025

Jordan Journal of Modern Languages and Literatures, Vol.16, No. 4

Faculty: Arts

Abstract: Résumé L’étude présente vise à souligner la double valeur du roman de Mohammed Becha, Wuhan ou la naissance de la Covid 19, en tant que document sérieux sur la pandémie du Covid-19, par sa référence aux informations scientifiques et histoire d’amour marquée à chaque pas par le poids lourd de cette pandémie. Elle souligne par conséquent l’interdépendance du réel et de l’imaginaire et le rôle de cet imaginaire dans l’animation du tableau réel d’une pandémie qui a actuellement un peu reculé mais qui perdure encore. Nous avons ainsi répondu aux questions suivantes : quelle est la valeur documentaire de ce roman sur la pandémie de Covid 19 ? Quelle est la part de l’imaginaire littéraire dans ce même roman qui, en réécrivant l’histoire documentée de cette pandémie, a narré en réalité une histoire d’amour placée sous le signe même de cette pandémie ?

Keywords: Covid-19, Pandémie, Imaginaire littéraire, Becha, Littérature francophone.

Research Title: Impact of Loads and Photovoltaic Uncertainties on Cascaded Failure in Transmission Networks of Future Power Grids

Author: Wasseem Hani Al Rousan, Published Year: 2025

IEEE Access, 13

Faculty: Engineering and Technology

Abstract: The increase investment of renewable energy resources (RESs) into power systems, such as solar photovoltaics (PVs), introduces additional uncertainty in transmission line loading. This uncertainty adds challenges to cascading failure analyses of power systems especially in future power scenarios of high penetration of RESs. In this paper, cascaded failures of power systems caused by the sequence tripping of transmission lines in the presence of RESs (mainly PV systems) is analyzed. By studying the lost power and the line failure probability, the potential impact of integrating more RESs on cascaded failures is investigated. In this regard, the uncertainties of RESs are examined by adding PV systems probability distribution function that reflects the solar irradiance for a typical day.A transmission-boosting approach is proposed in this paper to minimize the impact of failure risk to mitigate the possibility of the cascaded failure caused by the increased penetration of RESs. This paper presents a systematic approach to mitigate the risk of cascading failures via reconducting of transmission lines. Simulation studies for different penetration scenarios of PV systems have been carried out to test the impact on the cascaded failure and to validate the proposed transmission-boosting approach. The results in this paper imply that the increase in penetration of PV systems in the power grid would increase the potential of both cascaded failure risk and occurrence. In addition, the results have shown the efficacy of the proposed transmission-boosting approach in minimizing the cascaded failure risk when implemented. The findings have been validated using the modified version of the IEEE 39-bus test system modeled and simulated in Matlab.

Keywords: Cascaded failures , photvoltaic energy systems , steady-state analysis , transmission-boosting

Research Title: Stress levels and eating behavior among university students in Jordan: A cross‑sectional study

Author: Nour Ratib Batarseh, Published Year: 2024

Journal of Education and Health Promotion, 13

Faculty: Allied Medical Sciences

Abstract: Abstract: BACKGROUND: Increased body weight is common among university students; transitioning from high school to university may increase perceived stress levels, thus changing dietary habits and metabolism to promote overweight or obesity. The current study investigates the association between stress and dietary habits among university students in Jordan. MATERIALS AND METHODS: A cross‑sectional study was conducted among 221 university students aged between 20 and 25 at Applied Science Private University [ASU]. A self‑reported questionnaire was distributed to university students. The questionnaires were divided into three sections: the first was about general characteristics, body weight, change in body weight, and stress eating. RESULT: The survey of 208 participants showed that 64.3% were females, and 84.2% of students lived with their families. Results showed that more than half [51.1%] of the respondents were dissatisfied with their eating habits. Females [57.7%] monitored their food intake more than males did. However, most males [77.2%] reported less eating during stress compared to females. In addition, the data analysis revealed that those who ate more were less likely to monitor their food intake [χ² =9.734, df = 1, P = .002] or quantity [χ² =16.704, df = 1, P < .001]. Only 20.8% of the participants preferred sports or hobbies as a stress reduction activity; 29.4% took showers, while 51.1% ignored what made them stressed. Finally, 56.3% of participants reported increased weight after starting university, and it was significantly correlated with stress eating while studying for exams [χ² =8.762, df = 2, P = .013]. Stress affects university students and can lead to unhealthy eating habits and health issues like obesity. CONCLUSION: Many students face stress during their academic years, which affects their dietary choices. Policies promoting healthy eating habits and stress‑reducing activities are important for university students

Keywords: Dietary intake, obesity, stress eating, university student

Research Title: High-fat diet and related obesity provoke neurotoxins and alter neuro-biomarkers involved in Parkinson's disease

Author: Nour Ratib Batarseh, Published Year: 2023

obesity medicine , 41

Faculty: Allied Medical Sciences

Abstract: Abstract Introduction Parkinson's disease is considered one of the most important neurodegenerative diseases after Alzheimer's and is characterized by a complex pathological nature. Obesity is a highly prevalent disease that is key to many chronic diseases. Recent research has focused on the association between obesity, high-fat diets, neurotoxins, and Parkinson's disease. Objectives This review aimed to investigate the effect of a high-fat diet on Parkinson's biomarkers in the brain and the mechanisms by which obesity related to a high-fat diet provokes neurotoxins and proteins and contributes to the development of Parkinson's. Methods and materials Data were collected by searching literature published in PubMed, Science Direct, or registered in clinicaTrials.gov between April/2022 to September/2022. Full-text relevant original articles were included, which were published from 2000 to 2022. The exclusion criteria were abstracts, conference proceedings, case reports, and non-English language studies. Results and conclusion Studies have shown an association between a high-fat diet (40–60%) and the alteration in Parkinson's biomarkers in the brain. Obesity and high fat intake alter Parkinson's biomarkers, provoke neurotoxins, and induce neurotoxicity and degeneration of dopaminergic neurons within weeks or months. Also, findings showed that studies focused on certain biomarkers and fat percentages. However, many did not mention the amount and ratio of polyunsaturated fatty acids in the dietary intervention, which could be a potential contributor. Therefore, more research is required to provide information about all biomarkers, especially those shared with Alzheimer's, and the effect of polyunsaturated fatty acids on the neuroinflammation process.

Keywords: α-synuclein BDNF High fat Obesity Orexin Parkinson's

Research Title: Protective and Therapeutic Effects of Orlistat in Combination with Elettaria cardamomum “Cardamom” Extract on Learning, Memory, Anxiety, and Neuroinflammation in Obese Mice

Author: Nour Ratib Batarseh, Published Year: 2025

Medicina, 61

Faculty: Allied Medical Sciences

Abstract: Introduction and Objective: Obesity has increased worldwide, and existing anti-obesity medications have treatment limitations that diminish their overall benefits. This study aimed to investigate the effects of orlistat in combination with Elettaria cardamomum “Cardamom” (CAR) extract on working memory, recognition memory, anxiety, and inflammation within hippocampal tissue. Methods: Mice were categorized into two groups: a control group (CD) and a cafeteria diet (CAF) group induced with obesity (CAF) for 10 weeks. The groups were then subdivided into a CAF group treated with orlistat (CAF-ORL), a CAF group treated with orlistat and Elettaria cardamomum (CAF-ORL-CARD), and a group that continued on the CAF. The CAF-ORL group received orlistat at a dosage of 10 mg/kg/day for four weeks, while the CAF-ORL-CARD group received 10 mg/kg/day of orlistat and 500 mg/kg of CAR extract via oral gavage. In the 14th week, various assessments were conducted, including the novel object recognition (NOR) test, Y maze test, marble-burying test (MBT), open-field test, and TNF-α levels in the hippocampus. Result: TNF-α levels in the hippocampal tissue of the CAF group were elevated compared to the CD group (p < 0> 0.05). Conclusions: Orlistat combined with CAR has positive effects on neuroinflammation and memory, suggesting that this combination may offer potential therapeutic benefits for cognitive impairments and hippocampal dysfunction associated with obesity.

Keywords: learn; memory; orlistat; neuroinflammation; elettaria cardamomum

Research Title: The consequences of the Second Palestinian Intifada and its economic and social impact on the Palestinian people “2000-2005” - According to documentation from the Palestinian Central Bureau of Statistics

Author: Abdalla Ahmad Abdalla, Published Year: 2025

Faculty: Arts

Abstract: This study sheds light on the profound impacts of the Second Palestinian Intifada on the economic and social fabric of Palestinian society between 2000 and 2005. The study aims to quantify the Intifada’s effects across various units of the Palestinian community, by analyzing data from the Palestinian Central Bureau of Statistics and evaluating the dynamics of the impacts. The analyzed result indicated that the crisis exacerbated an existing economic crisis, resulting in deteriorating living conditions characterized by increased poverty and unemployment rates in Palestine. Consequently, Palestinians endured a prolonged excruciating hardship, with household incomes plummeting and the number of individuals living below the poverty line skyrocketing to an unimaginable figure. Unemployment rates surged by more than 27% on average, further exacerbating the socioeconomic challenges faced by the Palestinian population.

Keywords: The second Intifada, Palestinian economy, economic impact, history of the Intifada, social impact, unemployment

Research Title: Synthesis, Anticancer Screening, and In Silico Evaluations of Thieno[2,3-c]pyridine Derivatives as Hsp90 Inhibitors

Author: Balakumar Chandrasekarn, Published Year: 2025

Pharmaceuticals, 18

Faculty: Pharmacy

Abstract: Background: Thieno[2,3-c]pyridines and their analogs are not well explored for their anticancer properties. Hence, our research aimed to establish the anticancer potential of thieno[2,3-c]pyridines through cell-based assays and in silico evaluations. Methods: Thieno[2,3-c]pyridine derivatives 6(a–k) were synthesized and characterized using FT-IR, 1H-NMR, 13C-NMR, and HRMS. All the synthesized compounds were screened initially for their anticancer activity against MCF7 and T47D (breast cancer), HSC3 (head and neck cancer), and RKO (colorectal cancer) cell lines using MTT assay. Apoptosis and cell cycle analyses were conducted using Annexin V/propidium iodide (PI) double staining for apoptosis assessment and PI staining for cell cycle analysis to investigate the mechanisms underlying the reduced cell viability. In silico molecular docking was accomplished for the synthesized compounds against the Hsp90 and determined pharmacokinetics properties. Results: From the screening assay, compounds 6a and 6i were identified as potential inhibitors and were further subjected to IC50 determination. The compound 6i showed potent inhibition against HSC3 (IC50 = 10.8 µM), T47D (IC50 = 11.7 µM), and RKO (IC50 = 12.4 µM) cell lines, all of which indicated a broad spectrum of anticancer activity. Notably, 6i was found to induce G2 phase arrest, thereby inhibiting cell cycle progression. Molecular docking results indicated crucial molecular interactions of the synthesized ligands against the target Hsp90. Conclusion: The compound 6i induced cell death via mechanisms that are different from apoptosis. Thus, the synthesized thieno[2,3-c]pyridine derivatives can be suitable lead compounds to be optimized to obtain potent anticancer agents through Hsp90 inhibition.

Keywords: Hsp90; anticancer agents; thieno[2,3-c]pyridines; cell cycle analysis; molecular docking; ADME prediction

Research Title: Qualitative study of the experiences of caring of children living with End Stage Renal Disease'

Author: Maha Mohammed Wahbi Atout, Published Year: 2025

EAPC World Congress, Finland

Faculty: Nursing

Abstract: Background End-stage renal disease (ESRD) presents substantial challenges to children's well-being, imposing deleterious effects on daily functioning both for the child and the family. Overall, much is yet unknown about the lived experience of children with ESRD, although the literature identifies them as a population at psycho-emotional risk. Aim/Research question or hypothesis This study aims to understand the illness/caring experience of Jordanian children with ESRD from the perspectives of the children, their parents, and the health professionals (HCPs.) involved in their care Methods This research employed a qualitative descriptive methodology. Data was collected from several pediatric units in two hospitals in Amman, Jordan Results Individual, semi-structured, face-to-face interviews were conducted with four children with ESRD, eight mothers caring for a child with ESRD, four physicians, and five nurses who were involved in the care of children with ESRD. The collected data were analyzed using a thematic analysis strategy. The data obtained from the interviews were organized and contextualized into three major themes that reflected the prevailing experiences of the study participants: (1) Challenges faced by children, including suffering because of the dialysis, nutritional restrictions, long stay at hospital, and deprivation from school (2) Challenges faced by mothers, including economic challenges, the effect on other siblings, and feelings of restriction (3) Difficulties that HCPs encounter include parents' reactions to initial diagnoses and children's deaths. Discussion Parents, children, and HCPs. experience challenges as a result of the child illness with end stage renal disease. A primary responsibility of health care providers is to consistently advocate for children and families with a child suffering from ESRD and to devise strategies for implementing tailored interventions to aid these families in handling their complicated circumstances.

Keywords: Children, End Stage Renal Disease, qualitative study, carers

Research Title: The experience of nursing students and faculty with online teaching pedagogy: a qualitative study

Author: Maha Mohammed Wahbi Atout, Published Year: 2025

Teaching and learning in Nursing , 20

Faculty: Nursing

Abstract: Background: The worldwide shift towards online nursing education is rapidly growing. This transition requires more investigation to comprehend current situations and develop evidence-based approaches for online learning. Aim: To investigate the perspectives of nursing faculty and students regarding online education and to iden- tify any potential benefits it could provide to nursing education in the Occupied Palestinian Territory (OPT). Method: A qualitative explorative design was adopted whereby a purposive sample approach was utilized, and seven focus groups were conducted with undergraduate and graduate nursing students and nursing fac- ulty from two academic institutions. The derived data was analyzed using the theme analysis technique. Results: The study identifies three main themes: the potential of online teaching in nursing education, bene- fits of online education, and recommendations for successfully implementing online education in the Palesti- nian context. Conclusion: The study suggested that implementing online nursing education in the OPT context could be a significant advancement. However, it stresses the need for thorough planning and adequate resources to ensure its high quality and success in the OPT context.

Keywords: Nursing Education, Online Education, Pedagogy Qualitative Teaching

Research Title: Synthesis, Anticancer Screening, and In Silico Evaluations of Thieno[2,3-c]pyridine Derivatives as Hsp90 Inhibitors

Author: Mohammad Bayan, Published Year: 2025

Pharmaceuticals, 18

Faculty: Pharmacy

Abstract: Background: Thieno[2,3-c]pyridines and their analogs are not well explored for their anticancer properties. Hence, our research aimed to establish the anticancer potential of thieno[2,3-c]pyridines through cell-based assays and in silico evaluations. Methods: Thieno[2,3-c]pyridine derivatives 6(a–k) were synthesized and characterized using FT-IR, 1H-NMR, 13C-NMR, and HRMS. All the synthesized compounds were screened initially for their anticancer activity against MCF7 and T47D (breast cancer), HSC3 (head and neck cancer), and RKO (colorectal cancer) cell lines using MTT assay. Apoptosis and cell cycle analyses were conducted using Annexin V/propidium iodide (PI) double staining for apoptosis assessment and PI staining for cell cycle analysis to investigate the mechanisms underlying the reduced cell viability. In silico molecular docking was accomplished for the synthesized compounds against the Hsp90 and determined pharmacokinetics properties. Results: From the screening assay, compounds 6a and 6i were identified as potential inhibitors and were further subjected to IC50 determination. The compound 6i showed potent inhibition against HSC3 (IC50 = 10.8 µM), T47D (IC50 = 11.7 µM), and RKO (IC50 = 12.4 µM) cell lines, all of which indicated a broad spectrum of anticancer activity. Notably, 6i was found to induce G2 phase arrest, thereby inhibiting cell cycle progression. Molecular docking results indicated crucial molecular interactions of the synthesized ligands against the target Hsp90. Conclusion: The compound 6i induced cell death via mechanisms that are different from apoptosis. Thus, the synthesized thieno[2,3-c]pyridine derivatives can be suitable lead compounds to be optimized to obtain potent anticancer agents through Hsp90 inhibition.

Keywords: Hsp90; anticancer agents; thieno[2,3-c]pyridines; cell cycle analysis; molecular docking; ADME prediction